FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
LC3B
反应性
Human,Mouse,Rat
应用
WB,IF,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
14,16kD
推荐稀释比
WB 1:1000-2000;IHC 1:200-500;IF 1:200
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Polyclonal
免疫原
Recombinant Protein of MAP LC3β
特异性
The antibody detects endogenous MAP LC3β protein.
基因名称
MAP1LC3B
蛋白名称
Microtubule-associated proteins 1A/1B light chain 3B
别名
MAP1LC3B;MAP1ALC3;Microtubule-associated proteins 1A/1B light chain 3B;Autophagy-related protein LC3 B;Autophagy-related ubiquitin-like modifier LC3 B;MAP1 light chain 3-like protein 2;MAP1A/MAP1B light chain 3 B;MAP1A/MAP1B LC3 B;Microtubule-associated protein 1 light chain 3 beta
Organism-1
Human
基因ID-1
81631
SwissProt-1
Q9GZQ8
Organism-2
Mouse
SwissProt-2
Q9CQV6
Organism-3
Rat
SwissProt-3
Q62625
背景
The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasmic vesicle, autophagosome membrane ; Lipid-anchor . Endomembrane system ; Lipid-anchor . Mitochondrion membrane ; Lipid-anchor . Cytoplasm, cytoskeleton . Cytoplasmic vesicle . LC3-II binds to the autophagic membranes. LC3-II localizes with the mitochondrial inner membrane during Parkin-mediated mitophagy (PubMed:28017329). Localizes also to discrete punctae along the ciliary axoneme. .
