FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MEK-5
反应性
Human,Mouse,Rat
应用
WB,IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
49kD
推荐稀释比
WB 1:1000-2000;IHC 1:200-500;IF 1:50-200
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Polyclonal
免疫原
Recombinant Protein of MEK-5
特异性
The antibody detects endogenous MEK-5 protein.
基因名称
MAP2K5
蛋白名称
Dual specificity mitogen-activated protein kinase kinase 5
别名
MAP2K5;MEK5;MKK5;PRKMK5;Dual specificity mitogen-activated protein kinase kinase 5;MAP kinase kinase 5;MAPKK 5;MAPK/ERK kinase 5;MEK 5
Organism-1
Human
基因ID-1
5607
SwissProt-1
Q13163
Organism-2
Mouse
SwissProt-2
Q9WVS7
Organism-3
Rat
SwissProt-3
Q62862
背景
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011],
细胞定位
nucleus,cytoplasm,spindle,cytosol,
