NM23A Rabbit Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2607565

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商品描述
  • 靶点-Target

    NM23-H1

  • 反应性

    Human,Rat,Mouse

  • 应用

    IHC,IF

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    17kD

  • 推荐稀释比

    IHC 1:100-200;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Recombinant Protein of NM23A of NME1

  • 特异性

    NM23A protein detects endogenous levels of NME1

  • 基因名称

    NME1

  • 蛋白名称

    NME1

  • 别名

    NME1

  • Organism-1

    Human

  • 基因ID-1

    4830

  • SwissProt-1

    P15531

  • Organism-2

    Mouse

  • SwissProt-2

    P15532

  • Organism-3

    Rat

  • SwissProt-3

    Q05982

  • 背景

    This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cytoplasm . Nucleus . Cell-cycle dependent nuclear localization which can be induced by interaction with Epstein-barr viral proteins or by degradation of the SET complex by GzmA.