- 产品信息
商品描述
靶点-Target
SLUG
反应性
Human,Mouse,Rat
应用
WB,IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
30kD
推荐稀释比
WB 1:500-1000;IHC 1:200-500;IF 1:50-200
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Polyclonal
免疫原
Recombinant Protein of SLUG
特异性
The antibody detects endogenous SLUG protein.
基因名称
SNAI2
蛋白名称
Zinc finger protein SNAI2
别名
SNAI2;SLUG;SLUGH;Zinc finger protein SNAI2;Neural crest transcription factor Slug;Protein snail homolog 2
Organism-1
Human
基因ID-1
6591
SwissProt-1
O43623
Organism-2
Mouse
SwissProt-2
P97469
Organism-3
Rat
SwissProt-3
O08954
背景
snail family transcriptional repressor 2(SNAI2) Homo sapiens This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm. Observed in discrete foci in interphase nuclei. These nuclear foci do not overlap with the nucleoli, the SP100 and the HP1 heterochromatin or the coiled body, suggesting SNAI2 is associated with active transcription or active splicing regions.





