SLUG Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2607555

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商品描述
  • 靶点-Target

    SLUG

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    30kD

  • 推荐稀释比

    WB 1:500-1000;IHC 1:200-500;IF 1:50-200

  • 组成

    PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Polyclonal

  • 免疫原

    Recombinant Protein of SLUG

  • 特异性

    The antibody detects endogenous SLUG protein.

  • 基因名称

    SNAI2

  • 蛋白名称

    Zinc finger protein SNAI2

  • 别名

    SNAI2;SLUG;SLUGH;Zinc finger protein SNAI2;Neural crest transcription factor Slug;Protein snail homolog 2

  • Organism-1

    Human

  • 基因ID-1

    6591

  • SwissProt-1

    O43623

  • Organism-2

    Mouse

  • SwissProt-2

    P97469

  • Organism-3

    Rat

  • SwissProt-3

    O08954

  • 背景

    snail family transcriptional repressor 2(SNAI2) Homo sapiens This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Nucleus . Cytoplasm. Observed in discrete foci in interphase nuclei. These nuclear foci do not overlap with the nucleoli, the SP100 and the HP1 heterochromatin or the coiled body, suggesting SNAI2 is associated with active transcription or active splicing regions.