FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SOD1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
18kD
推荐稀释比
WB 1:500-1:2000;IHC:1:50-300;IF 1:50-200
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the Internal region of human SOD-1.
特异性
The antibody detects endogenous SOD1 protein.
基因名称
SOD1
蛋白名称
Superoxide dismutase [Cu-Zn]
别名
SOD1;Superoxide dismutase [Cu-Zn];Superoxide dismutase 1;hSod1
Organism-1
Human
基因ID-1
6647
SwissProt-1
P00441
Organism-2
Mouse
SwissProt-2
P08228
Organism-3
Rat
SwissProt-3
P07632
背景
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Mitochondrion . Nucleus . Predominantly cytoplasmic; the pathogenic variants ALS1 Arg-86 and Ala-94 gradually aggregates and accumulates in mitochondria. .
