FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TLR8
反应性
Human,Mouse,Rat
应用
IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
推荐稀释比
IHC 1:200-500;IF 1:50-200
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Polyclonal
免疫原
Recombinant Protein of TLR8
特异性
The antibody detects endogenous TLR8 protein.
基因名称
TLR8
蛋白名称
Toll-like receptor 8
别名
Toll-like receptor 8;CD288
Organism-1
Human
基因ID-1
51311
SwissProt-1
Q9NR97
Organism-2
Mouse
SwissProt-2
P58682
背景
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq, Jul 2008],
细胞定位
Endosome membrane ; Single-pass type I membrane protein . Endosomal localization confers distinctive proteolytic processing. .
