WIPI2 Rabbit Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2607542
- 产品信息
商品描述
靶点-Target
WIPI2
反应性
Human,Mouse,Rat
应用
IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
49kD
推荐稀释比
IHC 1:50-300;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Recombinant Protein of WIPI2
特异性
The antibody detects endogenous WIPI2 protein
基因名称
WIPI2 CGI-50
蛋白名称
WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2) (WIPI49-like protein 2)
别名
WD repeat domain phosphoinositide-interacting protein 2;WIPI-2;WIPI49-like protein 2;
Organism-1
Human
基因ID-1
26100
SwissProt-1
Q9Y4P8
Organism-2
Mouse
SwissProt-2
Q80W47
Organism-3
Rat
SwissProt-3
Q6AY57
背景
WD repeat domain, phosphoinositide interacting 2(WIPI2) Homo sapiens WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008],
细胞定位
Preautophagosomal structure membrane ; Peripheral membrane protein ; Cytoplasmic side . Localizes to omegasomes membranes which are endoplasmic reticulum connected structures at the origin of preautophagosomal structures. Enriched at preautophagosomal structure membranes in response to PtdIns3P. .





