α-tubulin Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

一键复制产品信息
产品规格:
  • 50μL
  • 100μL
货号:

FAB2607540

  • 产品信息
  • 注意事项
  • 实验验证
  • 产品声明
  • 引用文献
  • 相关产品
  • 文件下载
商品描述
  • 靶点-Target

    Tubulin α

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    52kD

  • 推荐稀释比

    WB 1:2000

  • 组成

    PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Polyclonal

  • 免疫原

    Recombinant Protein of Tubulin alpha-1A chain

  • 特异性

    The antibody detects endogenous α-tubulin protein.

  • 基因名称

    TUBA1A

  • 蛋白名称

    Tubulin alpha-1A chain

  • 别名

    YM3217

  • Organism-1

    Human

  • 基因ID-1

    7846;10376

  • SwissProt-1

    Q71U36;P68363

  • Organism-2

    Mouse

  • 基因ID-2

    22142;22143

  • Organism-3

    Rat

  • 基因ID-3

    64158;500929

  • SwissProt-3

    P68370;Q6P9V9

  • 背景

    Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.

  • 细胞定位

    Cytoplasm, cytoskeleton.