- 产品信息
商品描述
靶点-Target
IRE1α
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
105kD
推荐稀释比
WB 1:500-1:2000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Polyclonal
免疫原
Purified recombinant fragment of human IRE1α (aa282-433) expressed in E. Coli.
特异性
IRE1α Antibody detects endogenous levels of IRE1α protein.
基因名称
ERN1
蛋白名称
Serine/threonine-protein kinase/endoribonuclease IRE1
别名
ERN1;IRE1;Serine/threonine-protein kinase/endoribonuclease IRE1;Endoplasmic reticulum-to-nucleus signaling 1;Inositol-requiring protein 1;hIRE1p;Ire1-alpha;IRE1a
Organism-1
Human
基因ID-1
2081
SwissProt-1
O75460
Organism-2
Mouse
SwissProt-2
Q9EQY0
背景
The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq, Jul 2008],
细胞定位
Endoplasmic reticulum membrane ; Single-pass type I membrane protein .





