- 产品信息
商品描述
靶点-Target
UBQL1
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
65kD
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human UBQL1 AA range: 302-352
特异性
This antibody detects endogenous levels of human UBQL1
基因名称
UBQLN1 DA41 PLIC1
蛋白名称
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)
Organism-1
Human
基因ID-1
29979
SwissProt-1
Q9UMX0
Organism-2
Mouse
基因ID-2
56085
SwissProt-2
Q8R317
Organism-3
Rat
基因ID-3
56085
SwissProt-3
Q9JJP9
细胞定位
Cytoplasm . Nucleus . Endoplasmic reticulum . Cytoplasmic vesicle, autophagosome . Cell membrane . Detected in neuronal processes and at synapses (By similarity). Recruited to the ER during ER-associated protein degradation (ERAD) (PubMed:19822669). Isoform 1 and isoform 3 colocalize with PSEN1 in the cell membrane and in cytoplasmic juxtanuclear structures called aggresomes (PubMed:21143716). Colocalizes with ORAI1 and TICAM1 in the autophagosome (PubMed:23307288, PubMed:21695056). Colocalizes with EPS15 and HGS in ubiquitin-rich cytoplasmic aggregates that are not endocytic compartments and with EPS15 also in aggresomes (PubMed:16159959). .





