- 产品信息
商品描述
靶点-Target
RIF1
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
272kD
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human RIF1 AA range: 1428-1478
特异性
This antibody detects endogenous levels of human RIF1
基因名称
RIF1
蛋白名称
Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog)
Organism-1
Human
基因ID-1
55183
SwissProt-1
Q5UIP0
Organism-2
Mouse
基因ID-2
51869
SwissProt-2
Q6PR54
基因ID-3
51869
细胞定位
Nucleus . Chromosome . Chromosome, telomere . Cytoplasm, cytoskeleton, spindle . Following interaction with TP53BP1, recruited to sites of DNA damage, such as DSBs (By similarity). Exhibits ATM- and TP53BP1-dependent localization to uncapped or aberrant telomeres and to DNA double strand breaks (DSBs) (PubMed:15342490). Does not associate with normal telomere structures (PubMed:15342490, PubMed:15583028). Localizes to microtubules of the midzone of the mitotic spindle during anaphase, and to condensed chromosomes in telophase (PubMed:15583028). .





