FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
S12A1
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
121kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human S12A1 AA range: 595-645
特异性
This antibody detects endogenous levels of S12A1 at Human/Mouse/Rat
基因名称
SLC12A1 NKCC2
蛋白名称
S12A1
Organism-1
Human
基因ID-1
6557
SwissProt-1
Q13621
Organism-2
Mouse
基因ID-2
20495
SwissProt-2
P55014
Organism-3
Rat
SwissProt-3
P55016
背景
This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.[provided by RefSeq, May 2010],
细胞定位
Apical cell membrane ; Multi-pass membrane protein .
