FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
AT8A1
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
128kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human AT8A1 AA range: 159-209
特异性
This antibody detects endogenous levels of AT8A1 at Human/Mouse
基因名称
ATP8A1 ATPIA
蛋白名称
AT8A1
Organism-1
Human
基因ID-1
10396
SwissProt-1
Q9Y2Q0
Organism-2
Mouse
基因ID-2
11980
SwissProt-2
P70704
背景
The P-type adenosinetriphosphatases (P-type ATPases) are a family of proteins which use the free energy of ATP hydrolysis to drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily catalyzes transport of heavy metal ions. Another subfamily transports non-heavy metal ions (NMHI). The protein encoded by this gene is a member of the third subfamily of P-type ATPases and acts to transport amphipaths, such as phosphatidylserine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane ; Multi-pass membrane protein . Cytoplasmic granule . Cell membrane . Endoplasmic reticulum . Golgi apparatus . Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not TMEM30B (PubMed:20947505). In the presence of TMEM30A, predominantly located in cytoplasmic punctate structures and localizes to the plasma membrane (PubMed:20947505). Localizes to plasma membranes of red blood cells (By similarity). .
