FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SIAH1
反应性
Human,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
31kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human SIAH1 AA range: 157-207
特异性
This antibody detects endogenous levels of SIAH1 at Human/Rat
基因名称
SIAH1 HUMSIAH
蛋白名称
SIAH1
Organism-1
Human
基因ID-1
6477
SwissProt-1
Q8IUQ4
Organism-3
Rat
基因ID-3
140941
SwissProt-3
Q920M9
背景
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm. Nucleus. Predominantly cytoplasmic. Partially nuclear.
