FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SSRP1
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
78kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human SSRP1 AA range: 209-259
特异性
This antibody detects endogenous levels of SSRP1 at Human/Mouse/Rat
基因名称
SSRP1 FACT80
蛋白名称
SSRP1
Organism-1
Human
基因ID-1
6749
SwissProt-1
Q08945
Organism-2
Mouse
基因ID-2
20833
SwissProt-2
Q08943
Organism-3
Rat
基因ID-3
81785
SwissProt-3
Q04931
背景
The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Nucleus, nucleolus . Chromosome . Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci. .
