NLTP rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2606234

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商品描述
  • 靶点-Target

    NLTP

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    60kD

  • 推荐稀释比

    WB 1:500-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human NLTP AA range: 338-388

  • 特异性

    This antibody detects endogenous levels of NLTP at Human/Mouse/Rat

  • 基因名称

    SCP2

  • 蛋白名称

    NLTP

  • Organism-1

    Human

  • 基因ID-1

    6342

  • SwissProt-1

    P22307

  • Organism-2

    Mouse

  • 基因ID-2

    20280

  • SwissProt-2

    P32020

  • Organism-3

    Rat

  • 基因ID-3

    25541

  • SwissProt-3

    P11915

  • 背景

    This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.[provided by RefSeq, Aug 2010],

  • 细胞定位

    [Isoform SCP2]: Peroxisome . Cytoplasm . Mitochondrion . Endoplasmic reticulum . Mitochondrion .; [Isoform SCPx]: Peroxisome .