FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ASCC1
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
44kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human ASCC1 AA range: 289-339
特异性
This antibody detects endogenous levels of ASCC1 at Human/Mouse
基因名称
ASCC1 CGI-18
蛋白名称
ASCC1
Organism-1
Human
基因ID-1
51008
SwissProt-1
Q8N9N2
Organism-2
Mouse
基因ID-2
69090
SwissProt-2
Q9D8Z1
背景
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
细胞定位
Nucleus . Nucleus speckle . Colocalizes with PRPF8 in nuclear speckles in the absence of DNA damage. .
