FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
1C04
反应性
Human,Rat,Mouse,
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
40kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human 1C04 AA range: 110-160
特异性
This antibody detects endogenous levels of 1C04 at Human
基因名称
HLA-C HLAC
蛋白名称
1C04
Organism-1
Human
SwissProt-1
P30504
背景
HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described [provided by RefSeq, Jul 2008],
细胞定位
ane,extracellular region,endoplasmic reticulum,atus,plasma membrane,integral component of plasma membrane,cell surface,ER to port vesicle membrane,membrane,integral component of membrane,phaicle membrane,early endosome membrane,MHC class I protein complex,MHC class II protein complex,extracellular exosome,integral component of lumenal side of endoplasmic reticulum membrane,
