- 产品信息
商品描述
靶点-Target
TRAIP
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
52kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human TRAIP AA range: 399-449
特异性
This antibody detects endogenous levels of TRAIP at Human/Mouse
基因名称
TRAIP RNF206 TRIP
蛋白名称
TRAIP
Organism-1
Human
基因ID-1
10293
SwissProt-1
Q9BWF2
Organism-2
Mouse
基因ID-2
22036
SwissProt-2
Q8VIG6
背景
This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus, nucleoplasm . Nucleus, nucleolus . Chromosome . Cytoplasm. Cytoplasm, perinuclear region . In the nucleus, found in close proximity to PCNA, suggesting localization at replication foci (PubMed:26595769). Localizes to DNA damage sites in response to replication stress (PubMed:26781088, PubMed:26595769, PubMed:26711499). .





