FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CAPS1
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
149kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human CAPS1 AA range: 1275-1325
特异性
This antibody detects endogenous levels of CAPS1 at Human/Mouse/Rat
基因名称
CADPS CAPS CAPS1 KIAA1121
蛋白名称
CAPS1
Organism-1
Human
基因ID-1
8618
SwissProt-1
Q9ULU8
Organism-2
Mouse
基因ID-2
27062
SwissProt-2
Q80TJ1
Organism-3
Rat
基因ID-3
26989
SwissProt-3
Q62717
背景
This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described. [provided by RefSeq, Aug 2008],
细胞定位
Cell junction, synapse . Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle membrane ; Peripheral membrane protein . Membrane-associated to vesicles. Strongly enriched in synaptic fractions. Preferentially binds to dense core vesicles but not to synaptic vesicles. Binds phosphoinosides, with a strong selectivity for PtdIns(4,5)P2 over PtdIns(3,4,5)P3. Probably localizes to different vesicles compared to CADPS2. .
