COQ2 rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2606017

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商品描述
  • 靶点-Target

    COQ2

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    41kD

  • 推荐稀释比

    WB 1:500-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human COQ2 AA range: 160-210

  • 特异性

    This antibody detects endogenous levels of COQ2 at Human/Mouse/Rat

  • 基因名称

    COQ2 CL640

  • 蛋白名称

    COQ2

  • Organism-1

    Human

  • 基因ID-1

    27235

  • SwissProt-1

    Q96H96

  • Organism-2

    Mouse

  • 基因ID-2

    71883

  • SwissProt-2

    Q66JT7

  • Organism-3

    Rat

  • 基因ID-3

    498332

  • SwissProt-3

    Q499N4

  • 背景

    This gene encodes an enzyme that functions in the final steps in the biosynthesis of CoQ (ubiquinone), a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme, which is part of the coenzyme Q10 pathway, catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency, a mitochondrial encephalomyopathy, and also COQ2 nephropathy, an inherited form of mitochondriopathy with primary renal involvement. [provided by RefSeq, Oct 2009],

  • 细胞定位

    Mitochondrion inner membrane ; Multi-pass membrane protein ; Matrix side .