FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
FLNC
反应性
Human,Mouse
应用
IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
300kD
推荐稀释比
IHC 1:50-200;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human FLNC AA range: 335-385
特异性
This antibody detects endogenous levels of FLNC at Human/Mouse
基因名称
FLNC ABPL FLN2
蛋白名称
FLNC
Organism-1
Human
基因ID-1
2318
SwissProt-1
Q14315
Organism-2
Mouse
基因ID-2
68794
SwissProt-2
Q8VHX6
背景
This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Membrane ; Peripheral membrane protein . Cytoplasm, cytoskeleton . Cytoplasm, myofibril, sarcomere, Z line . A small amount localizes at membranes. In striated muscle cells, it predominantly localizes in myofibrillar Z lines, while a minor fraction localizes with subsarcolemme. Targeting to developing and mature Z lines is mediated by the intradomain insert.
