PDE6D rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2605928

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商品描述
  • 靶点-Target

    PDE6D

  • 反应性

    Human,Mouse

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    17kD

  • 推荐稀释比

    WB 1:500-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human PDE6D AA range: 89-139

  • 特异性

    This antibody detects endogenous levels of PDE6D at Human/Mouse

  • 基因名称

    PDE6D PDED

  • 蛋白名称

    PDE6D

  • Organism-1

    Human

  • 基因ID-1

    5147

  • SwissProt-1

    O43924

  • Organism-2

    Mouse

  • 基因ID-2

    18582

  • SwissProt-2

    O55057

  • 背景

    This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants. [provided by RefSeq, Mar 2014],

  • 细胞定位

    Cytoplasm, cytosol . Cytoplasmic vesicle membrane ; Peripheral membrane protein . Cytoplasm, cytoskeleton, cilium basal body .