FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
EXOC6
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
88kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human EXOC6 AA range: 610-660
特异性
This antibody detects endogenous levels of EXOC6 at Human/Mouse/Rat
基因名称
EXOC6 SEC15A SEC15L SEC15L1
蛋白名称
EXOC6
Organism-1
Human
基因ID-1
54536
SwissProt-1
Q8TAG9
Organism-2
Mouse
SwissProt-2
Q8R313
Organism-3
Rat
基因ID-3
50556
SwissProt-3
O54923
背景
The protein encoded by this gene is highly similar to the Saccharomyces cerevisiae SEC15 gene product, which is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast. It is one of the components of a multiprotein complex required for exocytosis. The 5' portion of this gene and two neighboring cytochrome p450 genes are included in a deletion that results in an autosomal-dominant form of nonsyndromic optic nerve aplasia (ONA). Alternative splicing and the use of alternative promoters results in multiple transcript variants. A paralogous gene encoding a similar protein is present on chromosome 2. [provided by RefSeq, Jan 2016],
细胞定位
Cytoplasm . Cytoplasm, perinuclear region . Cell projection, growth cone . Midbody, Midbody ring . Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation. Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214). .
