- 产品信息
商品描述
靶点-Target
NTCP2
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
38kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human NTCP2 AA range: 46-96
特异性
This antibody detects endogenous levels of NTCP2 at Human/Mouse/Rat
基因名称
SLC10A2 ASBT ISBT NTCP2
蛋白名称
NTCP2
Organism-1
Human
基因ID-1
6555
SwissProt-1
Q12908
Organism-2
Mouse
基因ID-2
20494
SwissProt-2
P70172
Organism-3
Rat
基因ID-3
29500
SwissProt-3
Q62633
背景
This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq, Mar 2010],
细胞定位
Membrane; Multi-pass membrane protein.





