- 产品信息
商品描述
靶点-Target
FAN
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
101kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human FAN AA range: 147-197
特异性
This antibody detects endogenous levels of FAN at Human/Mouse
基因名称
NSMAF FAN
蛋白名称
FAN
Organism-1
Human
基因ID-1
8439
SwissProt-1
Q92636
Organism-2
Mouse
基因ID-2
18201
SwissProt-2
O35242
背景
This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009],
细胞定位
cytoplasm,cytosol,endomembrane system,extrinsic component of membrane,





