FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TNNC1
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
18kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human TNNC1 AA range: 57-107
特异性
This antibody detects endogenous levels of TNNC1 at Human/Mouse
基因名称
TNNC1 TNNC
蛋白名称
TNNC1
Organism-1
Human
基因ID-1
7134
SwissProt-1
P63316
Organism-2
Mouse
基因ID-2
21924
SwissProt-2
P19123
背景
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008],
细胞定位
nucleoplasm,mitochondrion,cytosol,troponin complex,actin cytoskeleton,contractile fiber,
