- 产品信息
商品描述
靶点-Target
PDE4B
反应性
Human,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
81kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human PDE4B AA range: 103-153
特异性
This antibody detects endogenous levels of PDE4B at Human/Rat
基因名称
PDE4B DPDE4
蛋白名称
PDE4B
Organism-1
Human
基因ID-1
5142
SwissProt-1
Q07343
Organism-3
Rat
基因ID-3
24626
SwissProt-3
P14646
背景
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],
细胞定位
[Isoform PDE4B5]: Cytoplasm . Cell membrane .





