- 产品信息
商品描述
靶点-Target
CCD50
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
34kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human CCD50 AA range: 221-271
特异性
This antibody detects endogenous levels of CCD50 at Human/Mouse/Rat
基因名称
CCDC50 C3orf6
蛋白名称
CCD50
Organism-1
Human
基因ID-1
152137
SwissProt-1
Q8IVM0
Organism-2
Mouse
基因ID-2
67501
SwissProt-2
Q810U5
Organism-3
Rat
基因ID-3
288022
SwissProt-3
Q810U0
背景
This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008],
细胞定位
Cytoplasm. Associated with microtubules of the cytoskeleton and mitotic apparatus. .





