- 产品信息
商品描述
靶点-Target
HOME3
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
40kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human HOME3 AA range: 243-293
特异性
This antibody detects endogenous levels of HOME3 at Human/Mouse/Rat
基因名称
HOMER3
蛋白名称
HOME3
Organism-1
Human
基因ID-1
9454
SwissProt-1
Q9NSC5
Organism-2
Mouse
基因ID-2
26558
SwissProt-2
Q99JP6
Organism-3
Rat
基因ID-3
29548
SwissProt-3
Q9Z2X5
背景
This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009],
细胞定位
Cytoplasm . Cell junction, synapse, postsynaptic density . Cell junction, synapse . Postsynaptic density of neuronal cells. .





