FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ANO3
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
108kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human ANO3 AA range: 518-568
特异性
This antibody detects endogenous levels of ANO3 at Human/Mouse
基因名称
ANO3 C11orf25 TMEM16C GENX-3947
蛋白名称
ANO3
Organism-1
Human
基因ID-1
63982
SwissProt-1
Q9BYT9
Organism-2
Mouse
基因ID-2
228432
SwissProt-2
A2AHL1
背景
The protein encoded by this gene belongs to the TMEM16 family of predicted membrane proteins, that are also known as anoctamins. While little is known about the function of this gene, mutations in this gene have been associated with some cases of autosomal dominant craniocervical dystonia. Cells from individuals with a mutation in this gene exhibited abnormalities in endoplasmic reticulum-dependent calcium signaling. Studies in rat show that the rat ortholog of this protein interacts with, and modulates the activity of a sodium-activated potassium channel. Deletion of this gene caused increased pain sensitivity in the rat model system. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015],
细胞定位
Cell membrane ; Multi-pass membrane protein . Shows an intracellular localization. .
