FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
DHSO
反应性
Human,Mouse,Rat
应用
WB,IP
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
39kD
推荐稀释比
WB 1:500-2000;IP 1:200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human DHSO
特异性
This antibody detects endogenous levels of DHSO at Human/Mouse/Rat
基因名称
SORD
蛋白名称
DHSO
Organism-1
Human
基因ID-1
6652
SwissProt-1
Q00796
Organism-2
Mouse
基因ID-2
20322
SwissProt-2
Q64442
Organism-3
Rat
基因ID-3
24788
SwissProt-3
P27867
背景
Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010],
细胞定位
Mitochondrion membrane ; Peripheral membrane protein . Cell projection, cilium, flagellum . Associated with mitochondria of the midpiece and near the plasma membrane in the principal piece of the flagellum. Also found in the epididymosome, secreted by the epididymal epithelium and that transfers proteins from the epididymal fluid to the sperm surface. .
