- 产品信息
商品描述
靶点-Target
MTU1
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
46kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human MTU1 AA range: 368-418
特异性
This antibody detects endogenous levels of MTU1 at Human/Mouse/Rat
基因名称
TRMU MTU1 TRMT1
蛋白名称
MTU1
Organism-1
Human
基因ID-1
55687
SwissProt-1
O75648
Organism-2
Mouse
基因ID-2
72026
SwissProt-2
Q9DAT5
Organism-3
Rat
SwissProt-3
B1WC37
背景
This nuclear gene encodes a mitochondrial tRNA-modifying enzyme. The encoded protein catalyzes the 2-thiolation of uridine on the wobble positions of tRNA(Lys), tRNA(Glu), and tRNA(Gln), resulting in the formation of 5-taurinomethyl-2-thiouridine moieties. Mutations in this gene may cause transient infantile liver failure. Polymorphisms in this gene may also influence the severity of deafness caused by mitochondrial 12S ribosomal RNA mutations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
细胞定位
Mitochondrion .





