FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CCDB1
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
40kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human CCDB1 AA range: 53-103
特异性
This antibody detects endogenous levels of CCDB1 at Human/Mouse/Rat
基因名称
CCNDBP1 DIP1 GCIP HHM
蛋白名称
CCDB1
Organism-1
Human
基因ID-1
23582
SwissProt-1
O95273
Organism-2
Mouse
基因ID-2
17151
SwissProt-2
Q3TVC7
Organism-3
Rat
基因ID-3
362201
SwissProt-3
Q5BK06
背景
This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene. [provided by RefSeq, Apr 2009],
细胞定位
Cytoplasm. Nucleus.
