PSA6 rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2605684

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商品描述
  • 靶点-Target

    PSA6

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    27kD

  • 推荐稀释比

    WB 1:500-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human PSA6 AA range: 70-120

  • 特异性

    This antibody detects endogenous levels of PSA6 at Human/Mouse/Rat

  • 基因名称

    PSMA6 PROS27

  • 蛋白名称

    PSA6

  • Organism-1

    Human

  • 基因ID-1

    5687

  • SwissProt-1

    P60900

  • Organism-2

    Mouse

  • 基因ID-2

    26443

  • SwissProt-2

    Q9QUM9

  • Organism-3

    Rat

  • 基因ID-3

    29673

  • SwissProt-3

    P60901

  • 背景

    The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Aug 2013],

  • 细胞定位

    Cytoplasm . Nucleus . Translocated from the cytoplasm into the nucleus following interaction with AKIRIN2, which bridges the proteasome with the nuclear import receptor IPO9 (PubMed:34711951). Colocalizes with TRIM5 in cytoplasmic bodies (By similarity). .