FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
HEM1
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
70kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human HEM1 AA range: 87-137
特异性
This antibody detects endogenous levels of HEM1 at Human/Mouse/Rat
基因名称
ALAS1 ALAS3 ALASH OK/SW-cl.121
蛋白名称
HEM1
Organism-1
Human
基因ID-1
211
SwissProt-1
P13196
Organism-2
Mouse
基因ID-2
11655
SwissProt-2
Q8VC19
Organism-3
Rat
基因ID-3
65155
SwissProt-3
P13195
背景
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015],
细胞定位
Mitochondrion inner membrane ; Peripheral membrane protein . Localizes to the matrix side of the mitochondrion inner membrane. .
