FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PBIP1
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
80kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human PBIP1 AA range: 585-635
特异性
This antibody detects endogenous levels of PBIP1 at Human/Mouse/Rat
基因名称
PBXIP1 HPIP
蛋白名称
PBIP1
Organism-1
Human
基因ID-1
57326
SwissProt-1
Q96AQ6
Organism-2
Mouse
基因ID-2
229534
SwissProt-2
Q3TVI8
Organism-3
Rat
基因ID-3
310644
SwissProt-3
A2VD12
背景
The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined. [provided by RefSeq, Dec 2015],
细胞定位
Cytoplasm, cytoskeleton . Nucleus . Shuttles between the nucleus and the cytosol (PubMed:12360403). Mainly localized in the cytoplasm, associated with microtubules (PubMed:10825160, PubMed:12360403). Detected in small amounts in the nucleus (PubMed:10825160).
