FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NUDT5
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
24kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human NUDT5 AA range: 95-145
特异性
This antibody detects endogenous levels of NUDT5 at Human/Mouse/Rat
基因名称
NUDT5 HSPC115
蛋白名称
NUDT5
Organism-1
Human
基因ID-1
11164
SwissProt-1
Q9UKK9
Organism-2
Mouse
基因ID-2
53893
SwissProt-2
Q9JKX6
Organism-3
Rat
基因ID-3
361274
SwissProt-3
Q6AY63
背景
This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013],
细胞定位
Nucleus .
