FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
IFIX
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
54kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human IFIX AA range: 338-388
特异性
This antibody detects endogenous levels of IFIX at Human/Mouse
基因名称
PYHIN1 IFIX
蛋白名称
IFIX
Organism-1
Human
基因ID-1
149628
SwissProt-1
Q6K0P9
Organism-2
Mouse
基因ID-2
236312
SwissProt-2
Q8BV49
背景
The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2, which leads to stabilization of p53/TP53. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011],
细胞定位
[Isoform 1]: Nucleus, nucleoplasm.; [Isoform 3]: Nucleus, nucleoplasm.; [Isoform 5]: Nucleus. Nucleus speckle.
