FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
LRP5
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
178kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human LRP5 AA range: 1047-1097
特异性
This antibody detects endogenous levels of LRP5 at Human/Mouse
基因名称
LRP5 LR3 LRP7
蛋白名称
LRP5
Organism-1
Human
基因ID-1
4041
SwissProt-1
O75197
Organism-2
Mouse
基因ID-2
16973
SwissProt-2
Q91VN0
背景
This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],
细胞定位
Membrane ; Single-pass type I membrane protein . Endoplasmic reticulum . Chaperoned to the plasma membrane by MESD. .
