FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
AHR
反应性
Human,Mouse,Rat,Fish
应用
WB,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
93kD
推荐稀释比
WB 1:500-2000;IF/ICC1:100-500
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human AHR AA range: 408-458
特异性
This antibody detects endogenous levels of AHR at Human/Mouse/Rat
基因名称
AHR BHLHE76
蛋白名称
AHR
Organism-1
Human
基因ID-1
196
SwissProt-1
P35869
Organism-2
Mouse
基因ID-2
11622
SwissProt-2
P30561
Organism-3
Rat
基因ID-3
25690
SwissProt-3
P41738
背景
The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015],
细胞定位
Cytoplasm . Nucleus . Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus. .
