FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NUF2
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
51kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human NUF2 AA range: 199-249
特异性
This antibody detects endogenous levels of NUF2 at Human/Mouse/Rat
基因名称
NUF2 CDCA1 NUF2R
蛋白名称
NUF2
Organism-1
Human
基因ID-1
83540
SwissProt-1
Q9BZD4
Organism-2
Mouse
基因ID-2
66977
SwissProt-2
Q99P69
Organism-3
Rat
基因ID-3
304951
SwissProt-3
Q6AYL9
背景
This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus. Chromosome, centromere, kinetochore. Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore. NDC80 is required for efficient kinetochore localization.
