TRIM2 rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2605592

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商品描述
  • 靶点-Target

    TRIM2

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    82kD

  • 推荐稀释比

    WB 1:500-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human TRIM2 AA range: 162-212

  • 特异性

    This antibody detects endogenous levels of TRIM2 at Human/Mouse/Rat

  • 基因名称

    TRIM2 KIAA0517 RNF86

  • 蛋白名称

    TRIM2

  • Organism-1

    Human

  • 基因ID-1

    23321

  • SwissProt-1

    Q9C040

  • Organism-2

    Mouse

  • 基因ID-2

    80890

  • SwissProt-2

    Q9ESN6

  • Organism-3

    Rat

  • 基因ID-3

    361970

  • SwissProt-3

    D3ZQG6

  • 背景

    The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014],

  • 细胞定位

    Cytoplasm .