- 产品信息
商品描述
靶点-Target
TRIM2
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
82kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human TRIM2 AA range: 162-212
特异性
This antibody detects endogenous levels of TRIM2 at Human/Mouse/Rat
基因名称
TRIM2 KIAA0517 RNF86
蛋白名称
TRIM2
Organism-1
Human
基因ID-1
23321
SwissProt-1
Q9C040
Organism-2
Mouse
基因ID-2
80890
SwissProt-2
Q9ESN6
Organism-3
Rat
基因ID-3
361970
SwissProt-3
D3ZQG6
背景
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014],
细胞定位
Cytoplasm .





