- 产品信息
商品描述
靶点-Target
CPT1A
反应性
Human,Mouse,Rat,Canine
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
85kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human CPT1A. AA range 40-80
特异性
This antibody detects endogenous levels of CPT1A at Human/Mouse/Rat
基因名称
CPT1A CPT1
蛋白名称
CPT1A
别名
Carnitine O-palmitoyltransferase 1, liver isoform;CPT1-L;Carnitine O-palmitoyltransferase I, liver isoform;CPT I;CPTI-L;Carnitine palmitoyltransferase 1A;
Organism-1
Human
基因ID-1
1374
SwissProt-1
P50416
Organism-2
Mouse
基因ID-2
12894
SwissProt-2
P97742
Organism-3
Rat
基因ID-3
25757
SwissProt-3
P32198
背景
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion outer membrane ; Multi-pass membrane protein .





