- 产品信息
商品描述
靶点-Target
TLE3
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
85kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human TLE3 AA range: 257-307
特异性
This antibody detects endogenous levels of TLE3 at Human/Mouse/Rat
基因名称
TLE3 KIAA1547
蛋白名称
TLE3
别名
Transducin-like enhancer protein 3;Enhancer of split groucho-like protein 3;ESG3;
Organism-1
Human
基因ID-1
7090
SwissProt-1
Q04726
Organism-2
Mouse
基因ID-2
21887
SwissProt-2
Q08122
Organism-3
Rat
基因ID-3
84424
SwissProt-3
Q9JIT3
背景
This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013],
细胞定位
Nucleus.





