FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ADA11
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
85kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human ADA11 AA range: 600-650
特异性
This antibody detects endogenous levels of ADA11 at Human/Mouse
基因名称
ADAM11 MDC
蛋白名称
ADA11
别名
Disintegrin and metalloproteinase domain-containing protein 11;ADAM 11;Metalloproteinase-like, disintegrin-like, and cysteine-rich protein;MDC;
Organism-1
Human
基因ID-1
4185
SwissProt-1
O75078
Organism-2
Mouse
基因ID-2
11488
SwissProt-2
Q9R1V4
背景
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016],
细胞定位
Membrane; Single-pass type I membrane protein.
