FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NSUN2
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
85kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human NSUN2 AA range: 658-708
特异性
This antibody detects endogenous levels of NSUN2 at Human/Mouse
基因名称
NSUN2 SAKI TRM4
蛋白名称
NSUN2
别名
tRNA;cytosine;34;-C;5;-methyltransferase;Myc-induced SUN domain-containing protein;Misu;NOL1/NOP2/Sun domain family member 2;Substrate of AIM1/Aurora kinase B;tRNA;cytosine-5-;-methyltransferase;tRNA methyltransferase 4 homolog;hTrm4;
Organism-1
Human
基因ID-1
54888
SwissProt-1
Q08J23
Organism-2
Mouse
基因ID-2
28114
SwissProt-2
Q1HFZ0
背景
This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2011],
细胞定位
Nucleus, nucleolus . Cytoplasm . Mitochondrion . Cytoplasm, cytoskeleton, spindle . Secreted, extracellular exosome . Concentrated in the nucleolus during interphase and translocates to the spindle during mitosis as an RNA-protein complex that includes 18S ribosomal RNA (PubMed:19596847). In testis, localizes to the chromatoid body (By similarity). .
