- 产品信息
商品描述
靶点-Target
ECHA
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
85kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human ECHA AA range: 276-326
特异性
This antibody detects endogenous levels of ECHA at Human/Mouse/Rat
基因名称
HADHA HADH
蛋白名称
ECHA
别名
Trifunctional enzyme subunit alpha, mitochondrial;78 kDa gastrin-binding protein;TP-alpha;[Includes: Long-chain enoyl-CoA hydratase;Long chain 3-hydroxyacyl-CoA dehydrogenase;]
Organism-1
Human
基因ID-1
3030
SwissProt-1
P40939
Organism-2
Mouse
基因ID-2
97212
SwissProt-2
Q8BMS1
Organism-3
Rat
基因ID-3
170670
SwissProt-3
Q64428
背景
This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion . Mitochondrion inner membrane . Protein stability and association with mitochondrion inner membrane do not require HADHB. .





