FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SNX13
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
105kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human SNX13 AA range: 602-652
特异性
This antibody detects endogenous levels of SNX13 at Human/Mouse
基因名称
SNX13 KIAA0713
蛋白名称
SNX13
别名
Sorting nexin-13;RGS domain- and PHOX domain-containing protein;RGS-PX1;
Organism-1
Human
基因ID-1
23161
SwissProt-1
Q9Y5W8
Organism-2
Mouse
基因ID-2
217463
SwissProt-2
Q6PHS6
背景
This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008],
细胞定位
Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side .
