- 产品信息
商品描述
靶点-Target
TRI37
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
105kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human TRI37 AA range: 315-365
特异性
This antibody detects endogenous levels of TRI37 at Human/Mouse
基因名称
TRIM37 KIAA0898 MUL POB1
蛋白名称
TRI37
别名
E3 ubiquitin-protein ligase TRIM37;Mulibrey nanism protein;Tripartite motif-containing protein 37;
Organism-1
Human
基因ID-1
4591
SwissProt-1
O94972
Organism-2
Mouse
基因ID-2
68729
SwissProt-2
Q6PCX9
背景
This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. [provided by RefSeq, Mar 2016],
细胞定位
Cytoplasm, perinuclear region . Peroxisome . Found in vesicles of the peroxisome. Aggregates as aggresomes, a perinuclear region where certain misfolded or aggregated proteins are sequestered for proteasomal degradation. .





