TRI37 rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2605425

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商品描述
  • 靶点-Target

    TRI37

  • 反应性

    Human,Mouse

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    105kD

  • 推荐稀释比

    WB 1:500-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human TRI37 AA range: 315-365

  • 特异性

    This antibody detects endogenous levels of TRI37 at Human/Mouse

  • 基因名称

    TRIM37 KIAA0898 MUL POB1

  • 蛋白名称

    TRI37

  • 别名

    E3 ubiquitin-protein ligase TRIM37;Mulibrey nanism protein;Tripartite motif-containing protein 37;

  • Organism-1

    Human

  • 基因ID-1

    4591

  • SwissProt-1

    O94972

  • Organism-2

    Mouse

  • 基因ID-2

    68729

  • SwissProt-2

    Q6PCX9

  • 背景

    This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. [provided by RefSeq, Mar 2016],

  • 细胞定位

    Cytoplasm, perinuclear region . Peroxisome . Found in vesicles of the peroxisome. Aggregates as aggresomes, a perinuclear region where certain misfolded or aggregated proteins are sequestered for proteasomal degradation. .